Guide To Mesothelioma And Asbestos: The Intermediate Guide In Mesothelioma And Asbestos
Mesothelioma and Asbestos
Asbestos is a naturally occurring mineral that comes in thin, long fibres. People who are exposed to asbestos regularly are at risk of developing mesothelioma as well as other lung diseases of different types.
It can take years for symptoms to appear after asbestos exposure. Different asbestos types may cause different symptoms.
Pleural Mesothelioma
Pleural mesothelioma occurs in the lung's outer lining or the pleura. It is the most prevalent form of mesothelioma and accounts for 70% to 79% all diagnosed cases. Patients with this disease suffer from chest pain and shortness of breath and may also feel an ache or heaviness in the chest.
This type of cancer typically caused by exposure to asbestos, which is a collection of minerals comprised of microscopic fibres. These fibers, when inhaled cause irritation and DNA mutations. Pleura covers both the chest cavity as well as the lungs, so irritations can also affect the heart. Mesothelioma typically doesn't manifest until 30 to 50 years after exposure.
Shortness of breath and chest pain are the most frequently reported symptoms. Patients may also feel tightness in their chest or coughing. They may also experience difficulty breathing. People with this cancer often have previous exposure to asbestos in the workplace. The most prevalent jobs that put people at risk of developing pleural mesothelioma are manufacturing, construction, and shipbuilding. Individuals who have been in the military could be at an especially high risk due to the widespread use of asbestos in Navy vessels and bunkers for the army.
The most popular staging method for pleural mesothelioma is the TNM (tumor lymph nodes, lymph nodes and metastases) staging system. The stage a patient has upon diagnosis will assist their doctor in determining the best treatment plan for them. For instance, patients who have mesothelioma pleural stage three or four have a less favorable prognosis than those with lower stages. Mesothelioma in stage four is usually spread to the diaphragm, liver or even a person's heart. This could make the cancer more difficult to treat and increase the risk of complications for the patient.
Peritoneal Mesothelioma
As opposed to pleural mesothelioma that is a lung-lining cancer, peritoneal mesothelioma is found in the peritoneum, an elongated membrane that covers the abdominal cavity as well as organs such as the intestines and liver. Like pleural mesothelioma, peritoneal mesothelioma is triggered by asbestos exposure. Only 300-500 cases are diagnosed annually this is less than pleural asbestosis.
Like pleural mesothelioma, the symptoms can take years to show. Patients generally experience abdominal pain, and could also experience a mass in their abdomen. This mesothelioma type can also cause nausea, weight loss and fever. A lot of these symptoms are similar to those of gastrointestinal issues, which can lead to incorrect diagnosis.
Generally, doctors can find mesothelioma through an exhaustive medical history and physical exam. Imaging tests such as X-rays or CT scans are a way to identify mesothelioma. These tests can show tumors, as well as other signs of cancer that aren't visible on an X-ray.
These tests enable doctors to diagnose mesothelioma and determine the stage of the disease and suggest treatment options. The stage is determined by the type of cell as well as whether the tumor has spread.
The most important mesothelioma-related risk factor is asbestos exposure. People who have worked in jobs which require asbestos, like plumbing, manufacturing, electrical work or construction, are at increased risk of developing the disease. However, even if individuals do not work in these fields they could be exposed to asbestos through family members or through other sources. Anyone who believes they're at risk should consult an expert. A mesothelioma specialist can help those who have a experience with asbestos to understand more about their risk.
Risk Factors
Asbestos is the main risk factor for mesothelioma. It accounts for as much as the 80% of cases. Exposure to asbestos may occur through work, military service, or by living with someone who is exposed to asbestos or used to do the same. When exposed to asbestos compensation, particles are able to be inhaled into abdomen and lungs. These particles can cause irritation to the linings, causing cancerous cells to develop in the mesothelium. After exposure to asbestos, mesothelioma may occur between 15 and 60 years old.
Other risk factors include smoking, genetics and the advancing age. People in their 40s and 50s are more likely to be diagnosed with mesothelioma compared to those who are younger or older. Mesothelioma can take between 20 and 60 years to manifest cancer symptoms after the first exposure. It is important to keep in mind, too, that mesothelioma can develop in those who have been exposed to asbestos case, but without having worked with it directly. This is referred to as secondary or indirect asbestos exposure, and is as dangerous as direct asbestos exposure.
Smoking increases a person's chances of developing mesothelioma due to the fact that it damages the mesothelium, which makes it more susceptible to asbestos. Additionally, mesothelioma can be worsened by certain diseases like asbestosis and pneumonia. Men are more likely to develop mesothelioma than females. Men are more likely than women to have been exposed to asbestos case for longer periods of time and to have worked with asbestos for longer periods of time. Men are also more likely to have lived with someone who has been exposed to asbestos, and to have asbestos-containing fibers on their clothing. Women are less likely to come into contact with asbestos and rarely carry asbestos home on their clothes.
Diagnosis
It is difficult to recognize mesothelioma due to its symptoms being often similar to other conditions. Because of this, victims are often misdiagnosed.
The first step in diagnosing mesothelioma is for NYU Langone doctors to perform an examination and write notes on the medical history of a patient, including asbestos exposure. Doctors may also order an X-ray chest or CT scan to look for lumps and other abnormalities as well as evidence of previous asbestos exposure such as plaques in the pleura (thickened pleura with calcium deposits) and the buildup of fluid between the lung and chest wall (known as pleural effusion).
Other diagnostic tests include a magnetic resonance scan, or MRI test, which uses radio waves and magnets to create a series of detailed images of inside the body. Another way doctors can diagnose mesothelioma is by performing a surgical biopsy. When a biopsy is performed, doctors remove a tiny piece of tissue from pleura or the peritoneum, to be examined further. A pathologist will then look at the tissue with a magnifying glass to determine if it is a cancerous cells.
Mesothelioma can be classified based on the type of mesothelial cell involved, whether those cells are benign or malignant and also the location of the tumor, its type, and the stage of the tumor. Certain types of mesothelioma may be more likely to spread or metastasize which is why it is crucial to get a definite diagnosis to ensure that doctors are able to treat the disease before it becomes out of control.
Doctors can also perform laboratory tests on tumors in order to determine specific proteins, genes or other factors that will help them identify the characteristics of cancer and plan treatment. These results are known as staging.
Treatment
A mesothelioma diagnosis is an incredibly frightening prospect. However, it is important to remember that the disease is treatable, especially in its early stages. Many people with mesothelioma can live with the disease for a long time, without spreading.
Exposure to asbestos case can trigger mesothelioma via various mechanisms. Asbestos fibers that are too small to be felt or viewed by naked eyes, can become airborne and irritate the lining of the lung (pleura). As time passes irritation leads to formation of scar tissue, which can cause changes in the structure of cells that can eventually grow into tumors.
The Pleura is a covering that surrounds the abdomen, heart, and lungs. Mesothelium is composed of cells that react to asbestos, causing it to inflame and develop scar tissue. Overtime, these changes lead to the development of malignant mesothelioma tumors.
Shortness of breath, chest discomfort, or the accumulation of fluid on the lungs are all symptoms of the pleural mesothelioma. In rare cases the cancer may spread to the tissues surrounding the heart and reproductive organs.
A doctor will order biopsy if scans show the possibility of a lung tumor or stomach. During the procedure, doctors will remove a small sample of the fluid or tumor for laboratory testing. The results will confirm the diagnosis of mesothelioma and determine the best treatment option.
There are many types of mesothelioma treatment, including surgery, chemotherapy and immunotherapy. The majority of doctors employ the combination of these treatments. Participating in clinical trials of mesothelioma treatments may be beneficial for patients. Patients can find out more by consulting a mesothelioma expert who has treated the disease.