The Mesothelioma And Asbestos Case Study You ll Never Forget
Mesothelioma and Asbestos
Asbestos is a naturally occurring mineral that is made up of long, thin fibres. People who are regularly exposed to asbestos are at risk of developing lung diseases like mesothelioma.
Symptoms of these diseases may not show up for decades after exposure to asbestos. Different types of asbestos may cause different symptoms.
Pleural Mesothelioma
Pleural mesothelioma, a form of cancer, that develops in the outer lung the lining (pleura). It is the most frequent mesothelioma type, accounting for up 70 to 79% of diagnosed cases. The condition can cause chest discomfort, shortness of breath and a feeling of heaviness.
This type of cancer usually caused through exposure to asbestos, which is a collection of minerals comprised of microscopic fibres. These fibers, when inhaled can cause irritation and DNA mutations. The pleura is the area that surrounds the lungs and chest cavity, so these irritations can affect both the lungs and a person's heart. Mesothelioma symptoms are usually not apparent until 30 to 50 years after exposure.
Chest pain and shortness breath are the most common symptoms. Patients may also experience chest tightness and coughing, or breathing difficulties. People with this cancer often have previous exposure to asbestos in the workplace. The most prevalent jobs that expose people to the risk of developing pleural cancer are manufacturing, construction and shipbuilding. People who have served in the military may be at an especially high risk because of the extensive use of asbestos in Navy ships and bunkers for the army.
The most commonly used staging system for pleural mesothelioma is the TNM (tumor, lymph nodes and metastases) staging system. The stage that a patient is at upon diagnosis will assist their doctor in determining the most appropriate treatment plan for them. For instance, patients suffering from a pleural mesothelioma in stage three or four have a less favorable prognosis than patients with lower stages. Stage four mesothelioma is often spread to the diaphragm, liver or even a person's heart. This can make the cancer more difficult to treat and increase the risk of complications for the patient.
Peritoneal Mesothelioma
In contrast to pleural cancer, which is found in the lung's lining, peritoneal cancer develops in a membrane that surrounds the abdominal cavity, which includes organs like the intestines and liver. Like pleural mesothelioma, peritoneal mesothelioma is triggered by asbestos exposure. The disease is much less prevalent than pleural mesothelioma, and around 300-500 cases being diagnosed each year.
As with pleural asbestosis, symptoms can take a long time to manifest. Most patients suffer from abdominal pain and a mass in the abdomen. This kind of mesothelioma can cause nausea, weight loss and fever. Many of these symptoms can be mistaken for gastrointestinal problems and can lead to a misdiagnosis.
Doctors can detect mesothelioma by examining the patient's medical history and performing a physical examination. Imaging tests such as X-rays or CT scans are a way to identify mesothelioma. These tests can reveal tumors and other signs of cancer that are not evident on X-rays.
These test results enable doctors to diagnose mesothelioma and establish the stage. They can also recommend treatments. The stage is determined by the type of cell and whether the cancer has spread.
Asbestos exposure is the biggest risk factor. People who have been in occupations that involve asbestos, like plumbing or manufacturing, electrical work, or construction, are at a higher risk of developing the disease. Even if someone isn't employed in one of these fields they could be exposed to asbestos through family members or other sources. Anyone who suspects that they're at risk should speak with a doctor. A mesothelioma expert can help those who have had a previous history of asbestos to find out more about their risk.
Risk Factors
Asbestos exposure is the main risk factor for mesothelioma making up as much as 80 percent of cases. Exposure to asbestos can occur due to work, military service, or by living with a person who is exposed to asbestos law or was previously exposed to doing so. Asbestos particles can be inhaled by those who are exposed to it. These particles can cause irritation to the linings, causing cancerous cells to grow in the mesothelium. Mesothelioma may take between 15 and 60 years to develop following exposure to asbestos.
Other risk factors include smoking, genetics, and the advancing age. People in their 40s and 50s are more likely to get mesothelioma than people younger or more senior. This is because mesothelioma typically lasts between 20 and 60 years after the initial exposure to asbestos before the first signs of cancer appear. It is important to keep in mind, too, that mesothelioma could occur in those who have been exposed to asbestos case without having directly worked with it. This is referred to as secondary or indirect asbestos exposure and can be as hazardous as direct asbestos exposure.
Smoking can increase the likelihood of developing mesothelioma due to the fact that it causes mesothelium damage and makes it more susceptible to asbestos. Additionally, mesothelioma can be exacerbated by certain illnesses like pneumonia and asbestosis. Men are more likely to develop mesothelioma than women. This is due to men being more likely to be exposed to asbestos and endure a an extended period of exposure than women. Men are also more likely to live with someone who had asbestos exposure and bring stray asbestos legal fibers home on their clothes. Women are less likely to be exposed to asbestos, and they are less likely to bring asbestos case home on their clothes.
Diagnosis
It is difficult to recognize mesothelioma due to its symptoms being often similar to other diseases. This could lead to patients being wrongly diagnosed.
NYU Langone doctors will perform an examination of the body and document the patient's medical background including asbestos exposure. Doctors will also order an CT scan or chest X-ray to look for lumps, abnormalities and evidence of asbestos exposure. These include plaques in the pleura, thickened pleura and calcium deposits.
Other diagnostic tests include an echocardiogram which examines the blood vessels and the heart and magnetic resonance imaging, or MRI, test that uses radio waves and magnets to create precise images of the inside of the body. A surgical biopsy is another method for doctors to identify mesothelioma. A surgical biopsy is when doctors remove a small amount of tissue from the pleura or peritoneum for further testing. A pathologist can then examine the tissue under a magnifying glass to determine if it is a cancerous cells.
Mesothelioma can be classified based on the mesothelial type involved, whether the cells are benign or malignant and also the location, type, and stage of the tumor. Some types of mesothelioma are more likely to spread or metastasize which is why it is crucial to have a clear diagnosis so doctors can treat the disease before it becomes out of control.
Doctors can also perform laboratory tests on tumors in order to determine specific proteins, genes or other factors that will help them identify the characteristics of cancer and plan treatment. These results are known as staging.
Treatment
A diagnosis of mesothelioma may be frightening. But, it is crucial to keep in mind that the cancer can be treated, particularly in its earlier stages. Many patients with mesothelioma survive for many years with the disease, without spreading to other areas of their body.
Exposure to asbestos can cause mesothelioma in many ways. Asbestos fibers that are small enough to not be felt or seen through the naked eye are able to become airborne, irritating the lining of the lung (pleura). In time irritation leads to formation of scar tissue which causes changes in the structure of cells that can eventually grow into tumors.
The Pleura is a protective layer that covers the abdomen, heart, and lungs. Mesothelium is made up of cells that respond when exposed to asbestos. They cause inflammation to the tissue and cause it to scar. These changes can result in malignant mesothelioma tumors.
The symptoms of pleural mesothelioma are breathlessness, chest pain or the accumulation of fluid on the lung (pleural effusion). In rare instances, cancer can spread into the tissues that surround the reproductive organs and the heart.
A doctor will request biopsy if scans reveal a possible mass in the lungs or stomach. During the procedure, doctors will remove small amounts of the fluid or tumor for laboratory analysis. The results can confirm the diagnosis of mesothelioma, and also determine the best treatment plan.
There are many types of treatment for mesothelioma, such as chemotherapy and surgery. The majority of doctors use an amalgamation of these techniques. Patients could also benefit from enrolling in a clinical trial of new mesothelioma treatments. Patients can find out more by speaking with a mesothelioma doctor who has treated the disease.