The Mesothelioma And Asbestos Case Study You ll Never Forget
Mesothelioma and Asbestos
Asbestos is a natural mineral that is made up of thin, long fibres. Workers who are exposed to asbestos litigation regularly are at risk of developing mesothelioma as well as other types of lung diseases.
It can take years for symptoms to show up after asbestos exposure. Different asbestos types can cause different symptoms.
Pleural Mesothelioma
Pleural mesothelioma occurs in the lung's outer lining or pleura. It is the most frequent mesothelioma type, accounting for up between 70 and 79% of all diagnosed cases. Patients suffering from this condition feel chest pain and shortness of breath, and they may feel the sensation of weight in the chest.
This type of cancer is typically caused through exposure to asbestos, which is a cluster of minerals composed of microscopic fibers. Once inhaled, these fibers stick inside the lung and cause irritation which leads to scarring and DNA mutations. Pleura surrounds both the chest cavity and the lungs, so irritations can also affect the heart. Mesothelioma symptoms typically don't show until 30 to 50 years after exposure.
The most common symptoms of pleural melanoma are chest discomfort and shortness of breath. Patients may also feel tightness in their chest or coughing. They may also experience difficulty breathing. People who suffer from this cancer usually have previous exposure to asbestos in the workplace. The most common jobs that expose people to the risk of developing pleural mesothelioma are construction, manufacturing and shipbuilding. People who served in the military are at a greater risk due the frequent use of asbestos in Navy vessels and bunkers for the Army.
The TNM (tumors lymph nodes and metastases staging system) is the most commonly used staging system used to treat the pleural adenocarcinoma. The stage that a patient is in at the moment of diagnosis will determine the treatment plan they should follow. Patients with pleural mesothelioma that is in stage three or four will have a worse prognosis compared to those in a less advanced stage. Stage four mesothelioma is often spread to the liver, diaphragm or even a person's heart. This can make it more difficult to treat and increases the chance of complications for the patient.
Peritoneal Mesothelioma
As opposed to pleural mesothelioma that is a lung-lining cancer, peritoneal mesothelioma is found in the peritoneum -- a membrane that lines the abdominal cavity and organs like the intestines and liver. As with pleural mesothelioma asbestos exposure is the primary reason for peritoneal msothelioma. Only 300-500 cases are diagnosed each year which is lower than pleural asbestosis.
Like pleural mesothelioma, symptoms can take a long time to manifest. Patients typically have abdominal pain, and may have a mass in their abdomen. The symptoms of this type of mesothelioma can also include nausea or weight loss, as well as fever. A lot of these symptoms are similar to symptoms of digestive issues, which could lead to incorrect diagnosis.
Generally speaking, doctors can detect mesothelioma through a thorough health history and physical examination. Imaging tests like X-rays or CT scans can be used to identify mesothelioma. These tests can reveal tumors and other signs of cancer that aren't evident on X-rays.
These test results enable doctors to identify mesothelioma, and determine the stage. They can also suggest treatments. The stage is determined by the kind of cell and if the cancer has spread.
Asbestos exposure is the main risk factor. People who have worked in asbestos-related jobs, such as electrical or plumbing work, or in construction and manufacturing are more likely to contract the disease. Even if someone does not work in one of these fields however, they may be exposed to Asbestos Case (Zx.Greit.Si) through family members and other sources. Anyone who believes they're at risk should consult an expert. A mesothelioma specialist can assist those who have had a previous history of asbestos to find out more about their risk.
Risk Factors
Asbestos exposure is the main risk factor for mesothelioma, accounting for up to 80 percent of cases. Exposure to asbestos can occur due to work, military service, or by living with someone who is exposed to asbestos or has previously done so. Asbestos particles can be breathed in by those who are exposed to asbestos. These irritate the linings and trigger cancerous cells to grow in the mesothelium. Mesothelioma may take between 15 and 60 years to develop after exposure to asbestos.
Other risk factors include genetics, smoking and aging. People in their 40s and 50s are at greater chance of developing mesothelioma to those younger or older. It takes mesothelioma 20-60 years before it manifests cancer symptoms after the first exposure. It is important to remember that mesothelioma could occur in people who have been exposed to asbestos, but without having been directly exposed to it. This is known as secondary or indirect asbestos exposure. It can be as dangerous as direct asbestos law exposure.
Smoking increases the chance of mesothelioma developing, as it damages the mesothelium. It also makes it more susceptible. Mesothelioma can also be caused by certain diseases, such as asbestosis and pneumonia. It is also important to note that mesothelioma occurs more frequently for men than women. Men are more likely than women to have been exposed to asbestos for longer periods of time and to work with asbestos for longer periods of time. Men are also more likely to live with someone who had asbestos exposure and bring stray asbestos fibers home on their clothes. Women are less likely to come into exposure to asbestos and do not typically carry asbestos around on their clothes.
Diagnosis
Mesothelioma is difficult to diagnose because the symptoms are often similar to other conditions. Due to this, patients are often mistakenly diagnosed.
NYU Langone doctors will perform an examination of the body and document the patient's medical history including asbestos exposure. Doctors will also order a CT scan or chest X-ray in order to look for abnormalities, lumps and evidence of asbestos exposure. These include plaques in the pleura, thickened pleura and calcium deposits.
Other diagnostic tests include an echocardiogram, which examines the heart and blood vessels and magnetic resonance imaging, or MRI, test that uses radio waves and magnets to make a series of detailed images of the inside of the body. Another method doctors use to diagnose mesothelioma is by performing an operation called a biopsy. During a surgery biopsy, doctors remove a tiny part of tissue from the pleura or the peritoneum, to be tested further. A pathologist can then look at the tissue under microscopes to determine whether it contains cancerous cells.
Mesothelioma is classified according to the type of mesothelial cell involved, whether those cells are benign or malignant, and the location, type, and stage of the tumor. Some types of mesothelioma have an increased risk of spreading or metastasizing, so it's important to determine the type of mesothelioma to ensure that the doctors can treat it before it gets out of control.
Doctors can also perform laboratory tests on tumors to determine specific proteins, genes, or other factors which can aid in describing the characteristics of cancer and plan treatment. These results are known as staging.
Treatment
A diagnosis of mesothelioma can be a frightening prospect. It is important to keep in mind that cancer can be treated, particularly in its early stages. Many mesothelioma patients live for many years with the disease, without spreading to other organs of their body.
Exposure to asbestos law can cause mesothelioma through a variety of ways. Asbestos fibres, tiny enough to be felt or seen by naked eyes can be airborne, irritating the lining of the lung (pleura). In time, the irritation leads to the formation of scar tissues and eventually tumors.
The pleura is the area that surrounds the heart and lungs and the abdomen. Mesothelium is composed of cells that react to exposure to asbestos, causing it to inflame and form scar tissue. As time passes, these changes lead to the development of malignant mesothelioma cancers.
Shortness of breath, chest discomfort or fluid buildup on the lungs are all symptoms of pleural Msothelioma. In rare instances, cancer can spread into the tissues surrounding the reproductive organs as well as the heart.
A doctor may request biopsy if scans show a potential tumor in the lungs or stomach. During the procedure, doctors remove tiny amounts of fluid or tumor for lab analysis. The results can confirm a mesothelioma diagnosis, and determine the most effective treatment plan.
There are many types of mesothelioma treatments, which include chemotherapy, surgery, and immunotherapy. The majority of doctors use the combination of these methods. Enrolling in clinical trials of mesothelioma treatments that are new could be beneficial for patients. Patients can learn more about the trials by consulting a mesothelioma expert who has treated the condition.